Combining excellence in research and drug development to cure rare diseases worldwide
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Worldwide Health Challenge
350 million people across the globe have a rare disease, affecting 1 in 17 people during their life. Rare diseases disproportionately impact children, with a third of affected children dying before their fifth birthday. Patients with rare diseases, and their families, often have a long journey to diagnosis and little hope for a cure. Fewer than 5% of rare diseases have approved treatments. Powerful advances in DNA sequencing, scientific research and drug development will make curing rare diseases a reality.
"Our partnership with Harrington Discovery Institute recognises the combined experience needed in world-class science and drug development if we are to change the rare disease landscape in a meaningful way."
– Sir John Bell, University of Oxford
The University of Oxford and Harrington Discovery Institute, based at University Hospitals, Cleveland, Ohio, have formed a unique partnership combining world-leading strengths in research and therapeutics development, to form the Oxford-Harrington Rare Disease Centre (OHC). The OHC will set the science and innovation agenda, driving cutting-edge rare disease breakthroughs to address the unmet need in rare disease across the globe to deliver major clinical impact for patients.
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Since its founding in 2012, the Harrington Discovery Institute has supported more than 137 drugs-in-the-making across disease areas and academic institutions. HDI advances promising discoveries towards patients by aligning scientific and drug discovery expertise into a new model for accelerated drug development. The University of Oxford has a long history of research excellence and has more than 250 scientists working on over 350 rare diseases. In partnership, we aim to be the global leader in treating and eventually eliminating rare disease.